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The study was double-blinded. Patients were randomly assigned to receive placebo or active treatment once teva prednisone 50 mg tablet a week. The primary endpoint of study was the difference in number (baseline vs after 6 weeks of treatment) patients with severe osteoarthritis (defined as an arthralgia of at least 50 mm measured on a visual analogue scale of 0-100 mm) on a visual analogue scale of 0-25 mm, and the primary endpoint of study was the difference in number of participants with major adverse events (defined as an event that occurred in the treated group more than twice as often in the placebo group) during 6-week treatment period.
Primary outcome was assessed during the treatment phase, last 6 weeks of the open-label study. secondary outcome was assessed during the open-label study,
prednisone 50 mg tablet last 6 weeks of the double-blind study (6 weeks of treatment with placebo and then 12 weeks of treatment with active placebo). Participants were assessed at baseline, weeks 6 and 12 at the end of prednisone 20mg tablets watson double-blind study. Data were analysed by intention to treat using the approach and by intention to treat, with treat analyses also performed for the primary outcomes. Data were analysed by univariate analysis of variance and covariance, by using analysis of covariance in the intention to treat analyses.
AUTHORS' CONCLUSIONS:
Patients with osteoarthritis of any type showed less severe pain, arthralgia and knee instability with the use of online pharmacy berlin germany apo B-IV than with placebo. Based on these results, the authors recommend apo B-IV as a treatment option for patients with osteoarthritis of any type.
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